2.3 Daily Supplement Schedule

For best results, this schedule should be printed, laminated and ticked off with a whiteboard marker, each day.

Note that this schedule has been prepared using the custom troches and DIY "shake" and "sipper" recipes. Details for these can be found in the "4.2 Custom troches", "4.3 DIY shake and DIY sipper" and “5 Ordering products” sections.

These preparations significantly reduce the daily complexity and cost of the protocol, however it is also still possible to utilise individual supplements. Links to those products are also provided in “5 Ordering products”. 

However, if you aren't planning on using the custom troches, and / or DIY shake, you will instead need to optimally schedule a large array of individual products. (An alternative for the DIY sipper is not provided, or suggested.)

Details for these alternative schedule options are provided here:

2.3A Alternative daily supplement schedule - [no troches] - (if you intend on using the DIY shake recipe and not the custom troches)
2.3B Alternative daily supplement schedule - [no DIY shake]
- (if you intend on using the custom troches and not the DIY shake recipe)
2.3C Alternative daily supplement schedule - [no DIY shake or troches]
- (if you intend on not using the custom troches or the DIY shake)

.. please be aware, these schedules are considerably less convenient.

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Stage 1: Remineralisation, increasing collagen synthesis rates and performing a controlled initial “die-off”


This stage will typically last at least two weeks and can be initially unpleasant due to the microbial “die-off” effect – even though it is being minimised by various supplements.

If necessary, slow things down, as needed / use reduced doses and build up. If tolerated, 100mg/day aspirin can be helpful at this stage to help inflammation / hypoxia.

However, many items are complementary to each other, therefore moving too slowly during Stage 1 implementation may lead to an unsupported / unsustainable increase of immune activity, ultimately reducing energy availability and leading to lower glycogen and increased oxidative stress induced damage.


Stage 2: Increased GI / mucosal interventions


Whilst continuing all items from Stage 1, add the following elements. Note that the Stage 1 DIY sipper and shake recipes are replaced with a Stage 2 DIY sipper and shake recipes that contains additional ingredients.


Stage 2 is expected to trigger additional gastrointestinal immune activity, which is likely to be observed as diarrhoea lasting a few days and sometimes nausea.
Extra water and diosmectite / Diarelieve may be a useful binder during this time.
https://wikipedia.org/wiki/Diosmectite

Methylene blue is being tested as Stage 2 intervention.
https://bornfree.life/download/methylene_blue_protocol.xlsx

If your doctor has prescribed any anti-fungals and/or antibiotics, Stage 2 is the most appropriate place to introduce them.

However, these may have an impact on your existing efforts to restore microbiome diversity – some additional focus on probiotics, prebiotics and diet may be required. Ideally, any antibiotic use should be followed by Biomesight and/or other microbiome reports.

When you have completed Stage 2, repeat an Oligoscan / CMA test and don't proceed to Stage 3 until you have confirmed successful remineralisation. Similarly, iron status via standard pathology should be confirmed, if needed - iron, ferritin, transferrin saturation%, transferrin.


Stage 3: Stimulate and support a strong immune response


Important: confirm successful remineralisation of copper, zinc, selenium and manganese via CMA / Oligoscan and iron status via blood tests before proceeding to this stage.

This stage will typically require 4+ weeks.

If your cortisol / heart rate becomes elevated for long periods (>6 hours), or immune-related tissue pain/inflammation extends beyond 3 days per localised tissue, take a few days off the mushrooms, double the vitamin C and simultaneously decrease spirulina to 500mg during this “recovery break”. 100mg aspirin may again be helpful.

Expect temporary die-off symptoms, heavy immune response, pain / inflammation, POTS, fatigue, nausea, diarrhoea, headache, etc.

You will likely feel temporarily worse than your pre-protocol baseline, as the intensity of the innate immune response induces most of the ME/CFS symptoms. This may add some additional psychological challenges to this stage.

Continue items in all previous stages, apart from any minerals now measuring as “Normal+” on the Oligoscan report. Whilst continuing all Stage 1 and Stage 2 items, add the following elements. Note that the Stage 2 DIY sipper and shake recipes are replaced with a Stage 3 DIY sipper and shake recipes that contains additional ingredients.