Changelog
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| wdt_ID | wdt_created_by | Date | wdt_last_edited_by | wdt_last_edited_at | Ver | Rev | Type | Change | Description |
|---|---|---|---|---|---|---|---|---|---|
| 354 | 3dghs2 | 17/01/2026 | 3dghs2 | 17/01/2026 04:07 AM | 3.7 | Text | Update | Overhauled "2 The protocol" and related "Getting started" sections, for easier onboarding and clarity. The "Getting started" section content can now also be found on a stand-alone page (also in the website navigation menu), to reduce information overload. | |
| 353 | 3dghs2 | 15/01/2026 | 3dghs2 | 15/01/2026 06:37 AM | 3.7 | Text | Update | Added "daily" DIY sipper/shot recipe to the getting started daily run-sheet subsections, for simpler onboarding. Added reflux / vitamin U content to 2.2.3 Living without chronic dysbiosis. | |
| 352 | 3dghs2 | 14/01/2026 | 3dghs2 | 14/01/2026 05:09 AM | 3.7 | Text | Update | Integrated starting order (onboarding) groups into the daily run-sheets / schedules. | |
| 351 | 3dghs2 | 12/01/2026 | 3dghs2 | 12/01/2026 01:44 AM | 3.7 | Product | Addition | Resveratrol added back into the protocol for protection against excess lactic acid during onboarding electrolyte repletion and during metabolic stress. | |
| 350 | 3dghs2 | 09/01/2026 | 3dghs2 | 09/01/2026 04:14 AM | 3.7 | Product | Removed | Hesperidin removed from DIY shake recipe and main protocol pathway (replaced by MB microdosing). Can be used for specific hypometabolic events. | |
| 349 | 3dghs2 | 07/01/2026 | 3dghs2 | 07/01/2026 10:10 PM | 3.7 | Text | Update | Minor clarity updates. Corrected daily supplement schedule error - was missing Methylene Blue. | |
| 348 | 3dghs2 | 07/01/2026 | 3dghs2 | 07/01/2026 10:09 PM | 3.7 | Product | Source | Cobalt sources for US, EU, AU updated. | |
| 347 | 3dghs2 | 06/01/2026 | 3dghs2 | 06/01/2026 04:42 AM | 3.7 | Text | Update | Added content for fungi and metabolic acidosis to Gastrointestinal biofilms and pathogens subsection of 2.2.3 Living without chronic dysbiosis. | |
| 346 | 3dghs2 | 30/12/2025 | 3dghs2 | 30/12/2025 07:12 AM | 3.7 | Text | Update | Getting started section updated with downloadable daily schedules. Sympathetic overdrive section updated for clarity around influence of impaired nasal breathing + infection / inflammation. | |
| 345 | 3dghs2 | 22/12/2025 | 3dghs2 | 22/12/2025 12:20 PM | 3.7 | Text | Update | Updated the beginning of paragraph 2 in 2.2.4 The importance of “pacing” or “just enough activity” for clarity, as it was being misinterpreted widely that PEM was fear. Apologies for any confusion. | |
| 344 | 3dghs2 | 19/12/2025 | 3dghs2 | 19/12/2025 06:05 AM | 3.7 | Product | Addition | Inosine added to pre-protocol support and all stages. | |
| 343 | 3dghs2 | 18/12/2025 | 3dghs2 | 18/12/2025 12:32 PM | 3.7 | Tool | Update | Mosaic OAT Interpreter now works with the new v3 2025 report layouts. | |
| 342 | 3dghs2 | 29/11/2025 | 3dghs2 | 29/11/2025 02:19 AM | 3.7 | Text | Update | Uridine, Mg, P and carbohydrates added to rapid withdrawal support. 60-70% ethanol mentioned in DIY antiseptic subsection of 2.2.3 Living without chronic dysbiosis | |
| 341 | 3dghs2 | 28/11/2025 | 3dghs2 | 28/11/2025 03:01 AM | 3.7 | Text | Update | Your nervous system sends "predictions", not "facts" subsection added to 2.2.6 Cortisol, limbic system, glycogen and IFN-γ | |
| 340 | 3dghs2 | 24/11/2025 | 3dghs2 | 24/11/2025 04:58 AM | 3.7 | Text | Update | An easier onboarding process for ordering products, etc. can now be found in the Getting started subsection of "2 The protocol". | |
| 338 | 3dghs2 | 18/11/2025 | 3dghs2 | 18/11/2025 03:17 AM | 3.7 | Product | Addition | Uridine monophosphate added to sublingual dosing schedule, pre-protocol support. | |
| 339 | 3dghs2 | 18/11/2025 | 3dghs2 | 18/11/2025 03:17 AM | 3.7 | Product | Addition | D-ribose added to DIY sipper recipe and pre-protocol support. | |
| 337 | 3dghs2 | 17/11/2025 | 3dghs2 | 17/11/2025 03:09 AM | 3.7 | Text | Update | Updated DIY sipper, pre-protocol support and electrolytes sections to match monocalcium phosphate product upgrade. | |
| 336 | 3dghs2 | 17/11/2025 | 3dghs2 | 17/11/2025 03:08 AM | 3.7 | Product | Replace | Dicalcium phosphate upgraded to monocalcium phosphate for improved solubility and flavour, plus increased phosphate intake. | |
| 335 | 3dghs2 | 14/11/2025 | 3dghs2 | 14/11/2025 10:27 PM | 3.7 | Text | Update | Minor updates for clarity in pre-protocol and elecetrolytes section. | |
| 334 | 3dghs | 12/11/2025 | 3dghs | 12/11/2025 02:39 AM | 3.7 | Text | Update | Table of parasympathetic influences added to 2.2.6 Cortisol, limbic system, glycogen and IFN-γ, Sympathetic overdrive subsection. | |
| 333 | 3dghs | 10/11/2025 | 3dghs | 10/11/2025 07:11 AM | 3.7 | Text | Update | 2.2.6 Cortisol, limbic system, glycogen and IFN-γ updated, eATP P2X7 cascade added. | |
| 332 | 3dghs | 28/10/2025 | 3dghs | 29/10/2025 01:31 AM | 3.7 | Text | Update | Methylene Blue - "A lifeguard for the NAD+ pool" updated with guidance for non-responder / elevated oxidative-stress subgroup. Dropper bottle recipe instructions added. | |
| 331 | 3dghs | 01/10/2025 | 3dghs | 01/10/2025 10:38 AM | 3.7 | Text | Update | Theriome Aristotle and MosaicDX OAT interpreter tools released (see top menu). Oligoscan processor updated to v1.2.0. | |
| 330 | 3dghs | 15/09/2025 | 3dghs | 15/09/2025 07:27 AM | 3.7 | Text | Update | Minor adjustments to pre-protocol item inclusions / starting order. | |
| 329 | 3dghs | 03/09/2025 | 3dghs | 03/09/2025 06:56 PM | 3.7 | Text | Update | Gut subsection of Living without chronic dysbiosis updated around loss of butyrate producers. | |
| 328 | 3dghs | 03/09/2025 | 3dghs | 03/09/2025 06:56 PM | 3.7 | Product | Replace | Pendulum Akkermansia replaced with Pendulum Metabolic Daily, which includes butyrate producers. | |
| 327 | 3dghs | 27/08/2025 | 3dghs | 27/08/2025 04:22 AM | 3.7 | Text | Update | 4.3 DIY sipper - added suggestion for pouring "shots" of the sipper into a glass and topping up with water. | |
| 326 | 3dghs | 20/08/2025 | 3dghs | 20/08/2025 04:56 AM | 3.7 | Product | Source | Nootropics Depot NADH replaced with BulkSupplements NAD+ due to ongoing stock availability. ND NADH moved to ALT source. | |
| 325 | 3dghs | 11/08/2025 | 3dghs | 11/08/2025 02:14 AM | 3.7 | Text | Update | 7 new Acinetobacter species added to "fermenting species" database. General typography and grammar corrections. | |
| 324 | 3dghs | 03/08/2025 | 3dghs | 03/08/2025 07:34 AM | 3.7 | Text | Update | Numerous minor updates and edits for clarity. Figures on the disease model page linked from the protocol pages will now land directly. | |
| 323 | 3dghs | 31/07/2025 | 3dghs | 31/07/2025 06:17 AM | 3.7 | Text | Update | Mosaic DX TOXDetect (optional, recommended) subsection added to 2.1.3 Mosaic DX Organic Acids Test (OAT) | |
| 322 | 3dghs | 28/07/2025 | 3dghs | 28/07/2025 07:34 AM | 3.7 | Text | Update | 2.3.4 Rapid withdrawal symptoms, hypo/hyper-metabolism section updated with new diagrams, description of the process, interventions, expectations. | |
| 321 | 3dghs | 18/07/2025 | 3dghs | 18/07/2025 04:43 AM | 3.7 | Text | Update | Figure 18 added to disease model page. 2.3.2 Remineralisation updated and additional notes on iron supplementation added. 4.3 Compounded nutrients section renamed and updated. | |
| 320 | 3dghs | 12/07/2025 | 3dghs | 12/07/2025 07:37 AM | 3.7 | Text | Update | Corrected important typo in Methylene Blue - "A lifeguard for the NAD+ pool" - "0.1%" replaced with "1%" | |
| 319 | 3dghs | 11/07/2025 | 3dghs | 11/07/2025 08:10 AM | 3.7 | Text | Update | Acidaemia: a key influence in disease progression added to 2.2.4 The importance of “pacing” or “just enough activity”. Introduction text updated with CREB influence. | |
| 318 | 3dghs | 02/07/2025 | 3dghs | 02/07/2025 11:56 AM | 3.7 | Text | Update | Minor typographical errors corrected. Figure 17 added to Disease Model page. | |
| 317 | 3dghs | 27/06/2025 | 3dghs | 27/06/2025 01:38 AM | 3.7 | Text | Update | 2 - Pre-protocol support and starting order refined. | |
| 316 | 3dghs | 27/06/2025 | 3dghs | 27/06/2025 01:23 AM | 3.7 | Product | Replace | NAD+ and NMN replaced with sublingual NADH in main, pre-protocol support sections. | |
| 315 | 3dghs | 23/06/2025 | 3dghs | 23/06/2025 06:05 AM | 3.7 | Text | Update | Methylene Blue subsection updated, optimal dosing schedule refined. Figure 16 added. | |
| 314 | 3dghs | 15/06/2025 | 3dghs | 15/06/2025 06:36 AM | 3.7 | Text | Update | Onboarding sequence for severe patients updated in 2 The protocol. Figure 15 added to Disease Model page. | |
| 313 | 3dghs | 13/06/2025 | 3dghs | 13/06/2025 03:59 AM | 3.7 | Text | Update | Methylene Blue subsection updated for clarity and dosing schedule revised. | |
| 312 | 3dghs | 08/06/2025 | 3dghs | 08/06/2025 02:59 AM | 3.7 | Text | Update | NADPH: a reductive "currency", powered by TCA cycle flux subsection added to 2.2.4 The importance of “pacing” or “just enough activity” | |
| 311 | 3dghs | 06/06/2025 | 3dghs | 06/06/2025 10:56 PM | 3.7 | Text | Update | Methylene Blue - "A lifeguard for the NAD+ pool" subsection added to 2.3.1 Herxheimer / die-off / acetaldehyde support. Figure 14 added to Disease Model page. | |
| 310 | 3dghs | 30/05/2025 | 3dghs | 30/05/2025 03:25 AM | 3.7 | Text | Update | Note on carnosine added to 2.3.1 Herxheimer / die-off / acetaldehyde support. | |
| 309 | 3dghs | 25/05/2025 | 3dghs | 25/05/2025 12:18 PM | 3.7 | Text | Update | 2.2.1 Diet and 2.3.3 Blood-flow, hypoxia and fibrin-amyloid updated with notes around soy isoflavones that inhibit ALDH2, daidzin and daidzein. Figures 12 & 13 added to Disease Model page. | |
| 308 | 3dghs | 22/05/2025 | 3dghs | 22/05/2025 11:17 PM | 3.7 | Text | Update | 1 Introduction updated for clarity on lactic acidemia's role in the mineral depletion cascade. | |
| 307 | 3dghs | 22/05/2025 | 3dghs | 25/05/2025 12:19 PM | 3.7 | Product | Replace | Pre-protocol section - NMN replaced with NAD+. | |
| 306 | 3dghs | 21/05/2025 | 3dghs | 21/05/2025 05:20 AM | 3.7 | Text | Update | Recovering from severe metabolic and immune collapse (What it feels like and how to navigate the process) added to "1 Introduction." Figures 10 and 11 added to disease model. | |
| 305 | 3dghs | 17/05/2025 | 3dghs | 17/05/2025 03:24 AM | 3.7 | Text | Update | Histamine triggers glycogen redistribution subsection text added to 2.2.6 Cortisol, limbic system, glycogen and IFN-γ, 2.2.4 The importance of “pacing” or “just enough activity” and 2.2.9 PEM prevention and recovery. | |
| Date | Ver | Type |