2.1.3 Mosaic DX Organic Acids Test (OAT)
A Mosaic Diagnostics (Mosaic DX, formerly Great Plains) Organic Acids Test (OAT) is a comprehensive report on urine metabolites.
While there are various OAT vendors, eg. Genova Diagnostics, Vibrant, Nutripath, etc., the preferred vendor for this protocol is Mosaic DX, for reasons of reliability, results consistency and marker inclusion.
This test is available through local vendors, or these websites:
International - https://mosaicdxinternational.com/products/mx-organic-acids-test-oat
US -
1) https://www.integrativepsychiatry.net/shop/the-great-plains-laboratory/urine-organic-acids-test/
2) https://empowerednutrition.health/store/Mosaic-Diagnostics-Organic-Acid-Test-p523785023/ (US only)
UK - https://smartnutrition.co.uk/shop/great-plains-oat-organic-acids-test/
UK/EU - https://app.omnos.me/shop/tests/oat-organic-acid-test (needs practitioner)
EU - https://nordiclabs.com/EDetail.aspx?id=2878 (needs practitioner)
AU - via a RN Labs registered practitioner
NZ - https://store.stephenroigard.com/products/organic-acids-test
Note: if there is a pattern of “left shift” or “suspiciously
low” microbial markers on page 1 of the OAT results, it’s possible the
sample has thawed in transit and the integrity compromised, AND/OR the concentration of the sample was out of range (hydration levels). You may need
to repeat the test.
For best results a very short shipping time is
needed and creatinine levels (marker 77) should ideally be between 80-180 mg/dL.
Mosiac DX automatically scale the report markers against the creatinine levels, which can induce a false LEFT-shift with very high concentrations and RIGHT-shift with very low-concentrations. Overall, it's something I think the lab could improve on.
In addition to allowing interpretation of metabolic impairment from the patterns observed in these markers, page 1 of the report shows various markers for microbial interference. The remaining pages show your metabolic impairments from infection and malnutrition. Elevation of yeast, bacterial and fungal metabolites in OAT results have been seen consistently in our collected data, with matching symptoms. A further MycoTOX test may provide further clarity on species and expected metabolic impairments, if required.
A clinician’s guide to interpreting OAT results is being drafted. Example interpretations of these reports can be found on our Discord online discussion group.
A basic OAT interpretation guide for the purposes of supplement selection can be found in 4 Calculating supplement doses.