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I'd probably run the fast "clean" (apart from maybe a sprinkle of forskolin, caffeine if the HR spikes up when glycogen runs out) and during post-fast replenishment, look to also focus on drip-feeding riboflavin all-day, over a few days to a week, to help with digestion / absorption bottlenecks.
I do not think the protocol utilizes an excessive or noticeable amount of B6.
I had a B6 sample I wanted to take. So, I did the following:
- L-Ornithine ~375mg / day - 5 days (to lower Nitrogen, if present...sadly I am still waiting on LOLA...resorted to L-Ornithine / L-Arginine)
- EGCG 326mg / day - 10 days (Reishi and Beta Glucans introduced in the last ~3 days) alongside L-Ornithine
Note: EGCG and Reishi from Life Extensions source and also supported with sufficient B1, B2, and Mg
My B6 plasma sample came back and was a bit higher than I expected given my food tracking. It's impossible to be 100%, and there is some variability in foodstuffs, but a partial block of GDH should have generated a lot more B6 dependent enzyme activity and weighed against.
I did have what I believe to be characteristic liver pain in my upper right chest that I get during EBV outbreaks (well, what I "think" are EBV outbreaks), and my liver enzymes and GGT were elevated on the panel (see below). GGT being the biggest signal, IMO.
So, there was most certainly a reaction.

Regardless, I do plan on moving thru the EGCG fast as soon as I get all the ingredients (re-looking for succinate). Regardless of the B6 aspect, it does seem like the best way to "clean house".